Dampak Mutasi HMPV pada Pasien Kanker : Scoping Review

Shofi Marsya; Arvi Aliviani; Dian Tiranie; Elsa Vita; Levina Nabila; Shera  Aulia; Halimah Sadiyah; Gilang  Ramadhan; Ray Hanah; Zahra Aqiqah; Popi Sopiah

doi:10.51933/health.v10i1.1919

Dampak Mutasi HMPV pada Pasien Kanker : Scoping Review

Authors

Shofi Marsya Universitas Pendidikan Indonesia Kampus Sumedang
Arvi Aliviani Universitas Pendidikan Indonesia Kampus Sumedang
Dian Tiranie Universitas Pendidikan Indonesia Kampus Sumedang
Elsa Vita Universitas Pendidikan Indonesia Kampus Sumedang
Levina Nabila Universitas Pendidikan Indonesia Kampus Sumedang
Shera Aulia Universitas Pendidikan Indonesia Kampus Sumedang
Halimah Sadiyah Universitas Pendidikan Indonesia Kampus Sumedang
Gilang Ramadhan Universitas Pendidikan Indonesia Kampus Sumedang
Ray Hanah Universitas Pendidikan Indonesia Kampus Sumedang
Zahra Aqiqah Universitas Pendidikan Indonesia Kampus Sumedang
Popi Sopiah Universitas Pendidikan Indonesia Kampus Sumedang

DOI:

https://doi.org/10.51933/health.v10i1.1919

Keywords:

Mutasi HMPV, Kanker, Dampak

Abstract

Human Metapneumovirus (HMPV) adalah virus RNA dari keluarga Paramyxoviridae yang menyebabkan infeksi saluran pernapasan dan dapat mengalami mutasi, meningkatkan risiko penyakit serius. Penelitian ini bertujuan untuk menggambarkan dampak mutasi HMPV terhadap keparahan infeksi pada pasien kanker. Metode penelitian menggunakan scoping review dengan sumber data dari Google Scholar, PubMed, dan Semantic Scholar, menggunakan kata kunci mutasi HMPV, kanker, dan dampak. Kriteria inklusi mencakup artikel berbahasa Indonesia dan Inggris, pasien kritis, artikel full-text/open access, serta publikasi tahun 2015–2025 yang relevan dengan topik. Analisis dilakukan menggunakan diagram PRISMA untuk menyeleksi artikel yang sesuai. Hasil penelitian menunjukkan bahwa infeksi HMPV pada pasien kanker dapat memperburuk kondisi akibat penurunan sistem imun yang disebabkan oleh terapi kanker seperti kemoterapi atau transplantasi sel punca. Infeksi ini juga berisiko menimbulkan komplikasi serius, seperti pneumonia dan gagal napas, serta menghambat pengobatan kanker yang sedang berlangsung. Mengingat status imun yang terganggu, pasien kanker lebih rentan terhadap dampak mutasi virus ini. Oleh karena itu, penelitian lebih lanjut diperlukan untuk memahami konsekuensi klinis mutasi HMPV guna mengoptimalkan strategi pencegahan dan penanganan.

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Published

2025-06-25

How to Cite

Marsya, S., Aliviani, A., Tiranie, D., Vita, E., Nabila, L., Aulia, S. ., Sadiyah, H., Ramadhan, G. ., Hanah, R., Aqiqah, Z., & Sopiah, P. (2025). Dampak Mutasi HMPV pada Pasien Kanker : Scoping Review. Jurnal Kesehatan Ilmiah Indonesia (Indonesian Health Scientific Journal), 10(1). https://doi.org/10.51933/health.v10i1.1919

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Issue

Vol. 10 No. 1 (2025): Vol. 10 No. 1 Juni 2025

Section

Articles

License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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            PKPTemplateManager.display(frontend/pages/article.tpl) % line  297, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php

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                                                      SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[4], , null, null, 500, 1) % line  195, file: SubmissionSearch.inc.php
                                                   SubmissionSearch._getMergedPhraseResults(Object:Journal, Array[4], null, null, null, 500, 1) % line  147, file: SubmissionSearch.inc.php
                                                SubmissionSearch._getMergedKeywordResults(Object:Journal, Array[3], null, null, null, 500, 1) % line  133, file: SubmissionSearch.inc.php
                                             SubmissionSearch._getMergedArray(Object:Journal, Array[1], null, null) % line  264, file: SubmissionSearch.inc.php
                                          SubmissionSearch.retrieveResults(Object:Request, Object:Journal, Array[1], null, null, null, Object:DBResultRange, Array[1]) % line   92, file: RecommendBySimilarityPlugin.inc.php
                                       RecommendBySimilarityPlugin.callbackTemplateArticlePageFooter(Templates::Article::Footer::PageFooter, Array[3]) % line  107, file: HookRegistry.inc.php
                                    HookRegistry.call(Templates::Article::Footer::PageFooter, Array[3]) % line 1256, file: PKPTemplateManager.inc.php
                                 PKPTemplateManager.smartyCallHook(Array[1], Object:Smarty_Internal_Template) % line   43, file: a4fc84a2d9d2a85c011fcc528f09577e88e2fcff^1c372c95cd85572e0fbc9a53d0323a0b229cfc78_0.app.frontendpagesarticle.tpl.php
                              content_6a68177ce6b648_62335347(Object:Smarty_Internal_Template) % line  123, file: smarty_template_resource_base.php
                           Smarty_Template_Resource_Base.getRenderedTemplateCode(Object:Smarty_Internal_Template) % line  114, file: smarty_template_compiled.php
                        Smarty_Template_Compiled.render(Object:Smarty_Internal_Template) % line  216, file: smarty_internal_template.php
                     Smarty_Internal_Template.render(false, 1) % line  232, file: smarty_internal_templatebase.php
                  Smarty_Internal_TemplateBase._execute(Object:Smarty_Internal_Template, null, a4fc84a2d9d2a85c011fcc528f09577e88e2fcff, null, 1) % line  134, file: smarty_internal_templatebase.php
               Smarty_Internal_TemplateBase.display(frontend/pages/article.tpl, null, a4fc84a2d9d2a85c011fcc528f09577e88e2fcff, null) % line  924, file: PKPTemplateManager.inc.php
            PKPTemplateManager.display(frontend/pages/article.tpl) % line  297, file: ArticleHandler.inc.php
         ArticleHandler.view(Array[1], Object:Request) % line  391, file: PKPRouter.inc.php
      PKPRouter._authorizeInitializeAndCallRequest(Array[2], Object:Request, Array[1], false) % line  231, file: PKPPageRouter.inc.php
   PKPPageRouter.route(Object:Request) % line  143, file: Dispatcher.inc.php
Dispatcher.dispatch(Object:Request) % line  281, file: PKPApplication.inc.php
PKPApplication.execute() % line   68, file: index.php